An electrode system for cranial nerve stimulation includes a support coupling part for coupling a support. The support coupling part has a stimulating electrode insertion part formed to couple a stimulating electrode at the bottom thereof. The electrode system further includes an electrode holder formed to couple to a connecting wire for supplying electricity to the stimulating electrode, and an anchor having an electrode holder insertion part formed with a hollow part into which the electrode holder coupled to the connecting wire is inserted, and fixed to the skull of a subject.