Različica FHBP neisserie meningitidis in njena uporaba za cepljenje
- 专利权人:
- Oxford University Innovation Limited
- 发明人:
- TANG Christoph,LEA Susan
- 申请号：
- SI201331531
- 公开号：
- SI2887956T1
- 申请日:
- 2013.08.22
- 申请国别(地区):
- SI
- 年份:
- 2019
- 代理人:
- 摘要：
- The invention relates to a modified V2 fHbp having increased stability over a wild type V2 fHbp； a modified V2 fHbp having an amino acid sequence with at least 85% identity to the sequence of Seq ID No: 1, wherein both Ser137 and Gly138 are mutated or both Val112 and Leu114 are mutated； immunogenic, pharmaceutical and vaccine compositions； nucleic acid and a host cell； and methods of use of such compositions.
- 来源网站：
- 中国工程科技知识中心
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