A device for recovering one or more blastocysts from a uterus of a human includes an outer guide member for insertion into a cervical canal of the human. The outer guide member includes a distal portion with an activatable seal for isolating the uterus from the external environment. The outer guide member defines a lumen having a longitudinal axis. The device also includes an inner catheter located within the lumen and slidable along the longitudinal axis of the lumen relative to the outer guide member. The inner catheter has a distal tip positionable distally of the seal to extend into the uterus. The distal tip includes a semi-permeable absorbent head. The device defines a distal suction port for aspirating blastocysts from the uterus through the absorbent head.