UNIVERSIDADE DE LISBOA;FACULDADE DE FARMACIA DA UNIVERSIDADA DE LISBOA
发明人:
Lucilia Helena ATAIDE SARAIVA,Maria Manuel DUQUE VIEIRA MARQUES DOS SANTOS,Nuno Alexandre LOUSA PEREIRA,Clara Isabel FERREIRA PEREIRA,Sara GOMES MOREIRA,Mariana Valencia CASTANHEIRA FERREIRA LEAO,Ange
申请号:
US14901314
公开号:
US20160347765A1
申请日:
2014.06.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present application discloses novel family of Tryptophanol-Derived Oxazoloisoindolinones for use in the treatment of p53 associated conditions, such as cancer.These compounds are p53 activators and may be used in pharmaceutical compositions, alone or in combination with other chemoterapeutic agents.