The present invention relates to a method for manufacturing a compound of chemical formula 2, which is a production intermediate of an eribulin mesylate, in a high yield and high purity, and an intermediate for the same. According to the manufacturing method of the present invention, the compound of chemical formula 2, which is a production intermediate of the eriburin mesylate, can be produced with high yield and high purity.본 발명은 에리불린 메실산염의 제조 중간체인 화학식 2의 화합물을 고수율 및 고순도로 제조하는 방법 및 이를 위한 중간체에 관한 것이다.