Samuel Wright,Charles Shear,Denise D'Andrea,Andreas Gille,Danielle Duffy
申请号：
US16348106
公开号：
US20200038481A1
申请日:
2017.11.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Reconstituted HDL formulations, methods of treatment comprising same and uses thereof are provided for treating patients after an acute myocardial infarction (MI) event. The reconstituted HDL formulations comprise an apo lipoprotein, a lipid, a detergent and a stabilizer such as sucrose. Treatment of MI patients with repeated infusions of rHDL enhance cholesterol efflux capacity and do not produce significant alterations in liver or kidney function. The MI patient may have normal kidney function or moderate renal impairment.
