Novel forms of co-crystals of agomelatine and p-toluenesulphonic acid, method for preparing same and the pharmaceutical compositions containing same

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专利权人:

LES LABORATOIRES SERVIER;SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY

发明人:

Lynch, Michael,Letellier, Philippe,Shen, Yuhui,Shan, Hanbin,Luo, Ying

申请号：

NZ71615314

公开号：

NZ716153A

申请日:

2014.07.30

申请国别(地区):

NZ

年份:

2020

代理人:

摘要：

The present invention concerns forms of co-crystals of agomelatine and p-toluenesulphonic acid, the method for preparing same and the pharmaceutical compositions containing same. The co-crystals according to the invention have better solubility than agomelatine and are therefore more suitable for developing pharmaceutical compositions. They have a higher level of stability and purity, and are moreover obtained by a simple method that comprises no difficult steps.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/