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Small Molecule Activators of Parkin Enzyme Function
专利权人:
Mayo Foundation for Medical Education and Research
发明人:
Wolfdieter Springer,Fabienne C. Fiesel,Thomas R. Caulfield
申请号:
US16321208
公开号:
US20190169158A1
申请日:
2017.07.28
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to compounds for activating the enzymatic activity of an E3 ubiquitin ligase and methods for treating a disease or disorder in a subject with diminished E3 ubiquitin ligase enzymatic activity. In some embodiments, the present disclosure provides a compound of Formula (I) or a compound of Formula (II) or pharmaceutically acceptable salts thereof.
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