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Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use
专利权人:
AbbVie Overseas S.Á.R.L.;Galapagos NV
发明人:
Robert J. Altenbach,Andrew Bogdan,Sylvain Couty,Nicolas Desroy,Gregory A. Gfesser,Christopher Gaëtan Housseman,Philip R. Kym,Bo Liu,Thi Thu Trang Mai,Karine Fabienne Malagu,Nuria Merayo Merayo,Olivier
申请号:
US16878421
公开号:
US20200277274A1
申请日:
2020.05.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention discloses compounds of Formula (I),wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
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