Hans Van Eenennaam,Andrea Van Elsas,Joost Kreijtz,David Lutje Hulsik,Paul Vink
申请号：
US15665858
公开号：
US10808030B2
申请日:
2017.10.02
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to new anti-hCTLA-4 antibodies that bind to a different epitope than prior art anti-CTLA4 antibodies, methods to produce these antibodies and therapeutic and diagnostic uses of these antibodies. These antibodies show a similar affinity for the CTLA4 antigen and they are also able to block the binding of CTLA4 to CD80 and/or CD86.
