Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.
发明人:
申请号:
EP15743477.0
公开号:
EP3100731A1
申请日:
2015.01.22
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to a ligand-cytotoxic drug conjugate, preparation method and pharmaceutical use thereof. More specifically, the present invention provides a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D)n , their preparation method and use of the ligand-cytotoxic drug conjugate and a pharmaceutical composition containing the same in the preparation of a medicament for the treatment of cancer via receptor modulation.