Henry M. Kronenberg;John T. Potts, Jr.;Thomas J. Gardella
发明人:
Henry M. Kronenberg,John T. Potts, Jr.,Thomas J. Gardella
申请号:
US12376389
公开号:
US08143374B2
申请日:
2007.08.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is related to novel parathyroid hormone polypeptide derivatives, and to pharmaceutical composition containing the polypeptides, as well as synthetic and recombinant methods for producing the polypeptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing the polypeptides of the present invention. The present invention further provides diagnostic and therapeutic methods using the polypeptide derivatives.