Halogen-alkyl-1,3 oxazines as BACE1 and/or BACE2 inhibitors

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专利权人:

Thomas Woltering

发明人:

Thomas Woltering

申请号：

US14116043

公开号：

US08987255B2

申请日:

2012.06.04

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention provides compounds of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.

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