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DONEPEZIL-CONTAINING TRANSDERMAL ABSORPTION FORMULATION
专利权人:
TEIKOKU SEIYAKU CO.; LTD.
发明人:
KAWAKAMI, SATOSHI,YAMAJI, MASAHIRO
申请号:
SG2012025631
公开号:
SG179900A1
申请日:
2010.10.18
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
ABSTRACT DONFPFZIL-CONTAINING TRANSDERBIAI ABSORPTION FORMULATION5Provided is a donepezil-containing transdermal absorptionformulation that can sustainably administer donepezil for a long period of time, and can provide both a rapid increase in the blood level of donepezil and donepozil sustained release properties. The donepezil-containing transdermal absorption formulation is a10 transdermal absorption formulation produced by dissolving donepezil, which is the active ingredient, in an adhesive patch base that includes a hydrophobic polymer and an absorption promoter. The absorption promoter is one kind or two or more kinds selected from lauryl alcohol, triethyl citrate, isopropyl myristate, cetyl lactate,15 olevl alcohol, sorbitan monooleate, polyethylene glycol monostearate, lauromacrogol, N-methv1-2-pyrrolidone, and triacetin. Fig. 1
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