Joseph E. Payne,Padmanabh Chivukula,Steven P. Tanis
申请号:
US15224474
公开号:
US20170028074A1
申请日:
2016.07.29
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described herein is a compound having the structure of formula I, II, or III,wherein R comprises a double stranded RNA molecule, and L1, L2, and L3 independently for each occurrence comprise a ligand selected from the group consisting of a carbohydrate, a cholesteryl, or a peptide; a pharmaceutically accepted salt or pharmaceutical composition thereof; and a method of making the compound.