A method for displaying a sequence of fluoroscopic images of a subject defines, within the image area of a digital image receiver and in response to one or more viewer instructions, a region of interest and a background region that lies outside the defined region of interest. A succession of fluoroscopic images is obtained from the digital image receiver and, for image pixels within each of the succession of fluoroscopic images, background region pixel data are encoded and transmitted to the display apparatus using a lossy encoding. Region of interest pixel data is transmitted to the display apparatus using a lossless encoding. The succession of fluoroscopic images is displayed.