The invention belongs to pharmacology, and it can be used for making and treat and prevent the medicine of viral disease and viral infection immunity defect as caused by bleb, influenza, B-mode and HCV.Grass Gramineae sections Calamagrostis Adans belong to and/or Deshampsia Beauv belong to the bioactive substance extracted in green portion and small ear and contain flavone compound, that is tricin (tricin), apiolin, cyanidenon, Quercetin, rhamnazin flavonoids aglycon and/or tricin, apiolin, cyanidenon, Quercetin, rhamnazin flavonoid glycoside, auxiliary substance, composition (quality %) are as follows:Tricin flavonoids aglycon and/or its flavonoid glycoside 0.016 to 2.062%;Apiolin flavonoids aglycon and/or its flavonoid glycoside 0.010 to 1.393%;Cyanidenon flavonoids aglycon and/or its flavonoid glycoside 0.01 to 4.979%;Quercetin flavonoids aglycon and/or its flavonoid glycoside 0.001 to 0.771%;Rhamnazin flavonoids aglycon and/or its flavonoid glycoside 0.104 to 0.203%;Auxiliary substance 99.868 to 90.592%;To 0.203%;Auxiliary substance 99.868 to 90.592%.Therefore, the concrete activity material composition of biological active matter is determined, and its physical chemistry, biology performance allow to improve and select it that optimal components of antivirus action are played specific virus, formulation metering.In addition, it has been determined that derivant of this bioactive substance as (γ) type endogenous interferon, and there is apoptosis adjustment effect and antioxygenic property, improve stability of the cell to free radical pressure.Specific virus antivirus action is for herpes simplex types 2 virus, influenza virus, bovine diarrhea virus (HCV).