CLAIRE LOUISE ANDERTON,DAVID CLAPHAM,TREVOR RAYMOND KEEL,LEANDA JANE KINDON
申请号：
BRPI0713311
公开号：
BRPI0713311A2
申请日:
2007.06.20
申请国别(地区):
BR
年份:
2012
代理人:
摘要：
PYROLIDINE DERIVATIVES HAVING ACTIVITY IN GLYT1 CARRIER 2- (Methyloxy) - / V- [2-methyl-I-phenyl-2- (1-pyrrolidinyl) propyl] -4-succinate salts and napadisylates salts and solvates , 6-bis (trifluoromethyl) b enzamide, 6-bis (trifluoromethyl) benzamide, and their use in the treatment of GIyT1 transporter-related disorders such as schizophrenia is disclosed.DERIVADOS DE PIRROLIDINA TENDO ATIVIDADE NO TRANSPORTADOR DE GLYT1 São descritos sais de succinato e napadisilatos e solvatos de napadisilato de 2- (Metilóxi)-/V-[2-metiI-I-fenil-2-(1-pirrolidinil)propil]-4,6-bis(trifluormetil)b enzamida,6-bis(trifluormetil)benzamida, e é revelado o uso destes no tratamento de transtornos relacionados ao transportadores de GIyT1,tal como esquizofrenia.
