Washington State University;Baker Heart and Diabetes Institute
发明人:
RODGERS, Buel, Dantese,GREGOREVIC, Paul
申请号:
EP20160784014
公开号:
EP3285813(A4)
申请日:
2016.04.22
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia.