Metallocene Compounds and Labeled Molecules Comprising the Same for In Vivo Imaging

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专利权人:

APTENIA S.R.L.

发明人:

Guiseppe Zanoni,Alessio Porta,Marco Pazzi,Andrea Gandini,Wolfgang Karl-Diether Brill

申请号：

US14771462

公开号：

US20160008495A1

申请日:

2014.03.05

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention concerns compounds and methods of labeling peptides or other molecules with 18F or 19F or any other suitable radionuclide of use, for example, in PET or NMR in vivo imaging. A targeting molecule such as a protein or a peptide is linked to a substituted metallocene complex which is reacted with the 1gF or 19F shortly before performing the PET or NMR in vivo imaging on the patient. The labeled molecule is then used for targeting a cell, tissue, organ or pathogen to be imaged or detected.

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