THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
KOCHENDERFER, JAMES N.
申请号:
CA2951045
公开号:
CA2951045A1
申请日:
2015.06.01
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention is directed to a chimeric antigen receptor (CAR) directed against CD19, which comprises an amino acid sequence of any one of SEQ ID NO: 1- SEQ ID NO: 13. The invention also provides T-cells expressing the CAR and methods for destroying malignant B-cells.