QUART, BARRY,ROSENBAUM, DAVID,NEENAN, THOMAS,BLANKS, ROBERT
申请号:
NZ59574907
公开号:
NZ595749A
申请日:
2007.04.30
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
NZ 595749 Disclosed is the use of an inhibitor as defined herein for the manufacture of a medicament for the treatment of one or more d-IBS (diarrhoea-predominant irritable bowel syndrome) symptoms of diarrhoea, abnormal stool frequency, abnormal stool consistency or presence of urgency, wherein the inhibitor is selected from the group consisting of: an extract from Croton spp. or Calophyllum spp.; latex from Croton spp. or Calophyllum spp.; proanthocyanidin polymer composition from a Croton species or Calophyllum species; and crofelemer, wherein the amount of inhibitor is bioequivalent to crofelemer at a dosage of 50 mg per day to 750 mg per day.