Taekyu Lee,Nicholas F. Pelz,Johannes Belmar,Zhiguo Bian,Edward T. Olejniczak,Stephen W. Fesik,Brian A. Chauder
申请号：
US14429799
公开号：
US10093640B2
申请日:
2013.09.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein.
