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Fibrate-statin Combinations with Reduced Fed-fasted Effects
专利权人:
Pol-Henri Guivarch
发明人:
Pol-Henri Guivarch,Indu Parikh,Robert A. Snow
申请号:
US13295708
公开号:
US20120064160A1
申请日:
2011.11.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form of microparticles of solid fenofibrate that are stabilized by phospholipid as a surface active substance, wherein a therapeutically effective amount of the composition provides the statin and a quantity of fenofibrate to a fasted human patient that is greater than 80% of the quantity of fenofibrate provided by the same amount of the composition when administered to the same patient who has been fed a high fat meal.
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