isolated polypeptide, isolated polynucleotide, pharmaceutical composition, immunogenic composition, method for treating or preventing tuberculosis, and uses of a polypeptide, and a polynucleotide.
GLAXOSMITHKLINE BIOLOGICALS S.A.;GLAXO GROUP LIMITED
发明人:
DENNIS MURPHY,JAMES BROWN,PASCAL METTENS
申请号：
BRPI0916705
公开号：
BRPI0916705A2
申请日:
2009.07.24
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention is directed to a polypeptide which comprises: (i) an Rv1753c protein sequence； (ii) a variant of an Rv1753c protein sequence； or (iii) an immunogenic fragment of an Rv1753c protein sequence. In other aspects the invention is directed to associated polynucleotides, fusion proteins and methods for the treatment or prevention of tuberculosis.
