The present invention relates to a hollow fiber (HF) module having fibers modified with a thin film composite (TFC) layer comprising aquaporin water channels.本發明有關於一種中空纖維(HF)模組其具有經薄膜複合(TFC)層改質之纖維,其中該TFC層包含水通道蛋白水通道。(1)‧‧‧TFC層(2)‧‧‧支撐膜(3)‧‧‧單/雙層膜(4)‧‧‧水通道蛋白蛋白質