您的位置: 首页 > 农业专利 > 详情页

Temperature dependent activation of catalytic nucleic acids for controlled release
专利权人:
发明人:
JIANG GAO,MONIKA FISCHLER,VOLKER A ERDMANN
申请号:
IN5243/DELNP/2012
公开号:
IN2012DN05243A
申请日:
2012.06.13
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
THE PRESENT INVENTION RELATES TO AN ACTIVE SUBSTANCE RELEASE SYSTEM CONTAINING TWO COMPOUNDS. THE FIRST COMPOUND COMPRISES A NANOPARTICLE, COMBINED WITH AN OLIGONUCLEOTIDE INHIBITION STRAND THAT IS HYBRIDIZED WITH A CATALYTICALLY ACTIVE NUCLEIC ACID. THE SECOND COMPOUND COMPRISES A CARRIER, COMBINED WITH A SUBSTRATE MOLECULE THAT IS COUPLED TO A THERAPEUTIC ACTIVE SUBSTANCE. BY MEANS OF EXTERNAL STIMULATION, THE CATALYTICALLY ACTIVE NUCLEIC ACID OF THE FIRST COMPOUND IS RELEASED AND SPECIFICALLY BINDS TO THE SUBSTRATE MOLECULE OF THE SECOND COMPOUND. THIS LEADS TO CLEAVAGE OF THE SUBSTRATE MOLECULE, WHEREBY THE ACTIVE SUBSTANCE BOUND THERETO IS RELEASED.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充