[Problem] Provided is a guide wire capable of reducing an unintended deviation in a guide wire position while preventing an occurrence of discomfort with respect to usability.[Means for Resolution] The guide wire 10 has a flexible core wire 20, and has a distal core portion 34, a main body portion 30, and a rigidity changing portion 35 that gradually decreases in rigidity from the main body portion 30 toward the distal core portion 34. The rigidity changing portion includes a first tapered portion 31 continuous with a distal end of the main body portion, a second tapered portion 32 continuous with a distal end of the first tapered portion, and a third tapered portion 33 continuous with a proximal end of the distal core portion. A boundary portion 36 between the first tapered portion and the second tapered portion is located in a range of 300 to 400 mm from a foremost distal end of the distal core portion, and a gradient ((d12 - d11)/L1) of a change in a diameter d1 of the first tapered portion is larger than a gradient ((d22 - d21)/L2) of the change in a diameter d2 of the second tapered portion.
