The present invention provides a kind of drug for treating infectious diseases, preparation method and the usage, the drug is formed by radix scutellariae, cape jasmine, erigeron breviscapus and cholic acid compatibility, for key link-inflammatory reaction of infectious diseases, remove the harmful substances such as inflammatory mediator and free radical, improve local microcirculation state, to mitigate inflammatory pathologies damage, have the function of adjusting whole vivo environment simultaneously, lower respiratory tract infection and the acute lung injury by infection-induced can be effectively treated, and effective substance and the mechanism of action are relatively clear.本發明提供一種治療感染性疾病的藥物、其製備方法及用途,該藥物由黃芩、栀子、燈盞細辛和膽酸配伍而成,針對感染性疾病的中心環節-炎症反應,清除炎症介質和自由基等有害物質,改善局部微循環狀態,從而减輕炎症病理損傷,同時具有調節整體內環境的作用,能够有效治療下呼吸道感染以及由感染誘發的急性肺損傷,且藥效物質和作用機理相對清楚。