BHARAT LAGU,CHETAN PANDIT,MARK GARY BOCK,SANJITA SASMAL,THOMAS ULLRICH
申请号：
BR112014001751
公开号：
BR112014001751A2
申请日:
2012.07.25
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract the invention relates to a compound of formula (i) in free form or in pharmaceutically acceptable salt form (i) in which the substituents are as defined in the specification； to its preparation, to its use as a medicament and to medicaments including it. the present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. -------------------------------------------------- ----------------------------- Translation of Abstract Patent Summary: "Pyrazoline derivatives and their use as selective modulators of the receptor for estrogen ". It is the compound of formula (i) in free form or in pharmaceutically acceptable salt form (i) wherein the substituents are as defined in the specification； of its preparation, and its use as a medicine and of medicines that comprise the same. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.abstract the invention relates to a compound of formula (i) in free form or in pharmaceutically acceptable salt form (i) in which the substituents are as defined in the specification； to its preparation, to its use as a medicament and to medicaments comprising it. the present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. ------------------------------------------------------------------------------- tradução do resumo resumo patente de invenção: "derivados de pirazolina e seu uso como moduladores seletivos do receptor de estrogênio". trata-se do composto da fórmula (i) sob a forma livre ou sob a forma de sal farmaceuticamente aceitável (i) em que os substituintes são conforme definido no relatório descritivo； de sua preparação, e seu uso como um medicamento e de medicamentos que compreendem o mesmo. a presente invenção proporciona ainda uma com-binação de agentes farmacologicamente ativos e uma composição farmacêutica.
