PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF

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专利权人:

APOTEX PHARMACHEM INC

发明人:

BODHURI, PRABHUDAS,WEERATUNGA, GAMINI

申请号：

NZ59594210

公开号：

NZ595942A

申请日:

2010.04.28

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

595942 Disclosed herein is a process for the preparation of S-Rivaroxaban (1) and/or R-Rivaroxaban comprising reacting, in the presence of a first base such as a strong base suitable for deprotonation of an amide, a compound of Formula 9 with a compound of Formula 8. Additionally disclosed are intermediates useful in the preparation of S-Rivaroxaban (1) and/or R-Rivaroxaban.

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中国工程科技知识中心

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http://www.ckcest.cn/home/