6-BENZYL-6H-THIENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-ONE DERIVATIVES AS PHOSPHODIESTERASE-1 (PDE-1) INHIBITORS FOR THE TREATMENT OF E.G. NEUROLOGICAL, COGNITIVE AND CARDIOVASCULAR DISORDERS
Described herein are compounds of Formula I and Formula II, methods of their synthesis, compositions comprising the compounds, and use of the compounds and compositions in treating numerous diseases and disorders, including cognitive deficits associated with CNS diseases and disorders.