Described herein are block copolymers having hydrophobic blocks and hydrophilic blocks which are effective in binding to the surface of hard tissue; compositions comprising the same, as well as methods of making and using the same.本發明敘述具有疏水性嵌段與親水性嵌段之嵌段共聚物,其可有效性結合至硬組織的表面;包含該嵌段共聚物之組成物,以及製作及使用該嵌段共聚物之方法。