Controlled release pharmaceutical compositions of tapentadol

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专利权人:

Lupin Limited

发明人:

Deshmukh, Ashish Ashokrao,Bhutada, Pravin Meghrajji,Chandran, Sajeev,Kulkarni, Shirishkumar

申请号：

AU2011236548

公开号：

AU2011236548A1

申请日:

2011.02.07

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

A once daily controlled release pharmaceutical compositions comprising tapentadol, wherein preferably the mean T of tapentadol is reached after 10 hours of administration of the composition. The composition comprises tapentadol, such that it maintains serum concentration of tapentadol of at least about 20 ng/ml for at least about 17 hours after oral administration of the composition. According to one embodiment the controlled release pharmaceutical composition comprises tapentadol, which is gastroretentive.

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