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FARMACEUTSKI PRIPRAVAK ZA ORALNU PRIMJENU
专利权人:
Astellas Pharma Inc.
发明人:
Yasuji, Takehiko,Kinoshita, Noriyuki,Yoshino, Hiroyuki,Kawahama, Shuuya,Sako, Kazuhiro,Sugihara, Akio
申请号:
HRP20161138
公开号:
HRP20161138T1
申请日:
2016.09.06
申请国别(地区):
HR
年份:
2016
代理人:
摘要:
The present invention relates to a pharmaceutical composition for oral administration comprising a modified release portion containing tamsulosin or a pharmaceutically acceptable salt thereof, and an immediate release portion containing solifenacin or a pharmaceutically acceptable salt thereof and a hydrophilic substance. In the pharmaceutical composition, the dissolution rate of each drug (in particular, solifenacin contained in the immediate release portion) is similar to those of the current single drug formulations, and the maximum percentage of drag dissolution of each drug (in particular, solifenacin contained in the immediate release portion) is 90% or more. Therefore, the pharmaceutical composition is a single formulation (i.e., a combined formulation) with a bioavailability equivalent to those of the current single drug formulations.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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