A method of controlling a reduced-pressure treatment system, the method comprising:supplying reduced pressure to a reservoir (230);monitoring a pressure signal (246) correlated to reduced pressure within the reservoir;receiving a supply signal (254) correlated to a supply rate of reduced pressure;determining if a blockage condition exists based on the pressure signal and the supply signal; andterminating the supply of reduced-pressure if the blockage condition exists;wherein the reduced pressure is supplied with a vacuum pump (248) and determining if theblockage condition exists comprises determining if the pressure signal decreases below a selected absolute value for a specified time interval and the pressure signal does not rise in absolute value with an increased supply signal.