A method and system for intra-oral imaging using High Dynamic Range (HDR) and highlight removal is presented. The method comprising generating a first High HDR irradiation map of teeth with multiple images captured with different exposures for same intra-oral scene and removing highlight caused by a specular reflection in a detail-reserved way from the first HDR irradiation map so as to obtain a second HDR irradiation map in which the specular reflection is at least partly suppressed.