SHOW-WEN LIU,YU CHANG,CHENG-FANG HSU,TSUNG-HSIEN CHIANG,SHENG-LUN LIN,CHIH-YUAN LIN
申请号：
US13920364
公开号：
US20140371434A1
申请日:
2013.06.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A radiotracer precursor for imaging of hypoxic tissues, a radiotracer and a method for preparing the same are revealed. The radiotracer precursor, DANI, includes a nitroimidazole functional group with a feature of retention in hypoxic tissues and a bifunctional ligand able to complex with radioisotopes. Thus DANI can be used to produce radiotracers stayed in hypoxic tissues and the radiotracers are applied to medical imaging of malignant tumor with hypoxic layer.
