INHIBITEURS DE KINASES THIAZOLES ET OXAZOLES

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专利权人:

AB SCIENCE

发明人:

MOUSSY, ALAIN,BENJAHAD, ABDELLAH,MARTIN, JASON,CHEVENIER, EMMANUEL,PEZ, DIDIER,SANDRINELLI, FRANCK,PICOUL, WILLY

申请号：

CA2786800

公开号：

CA2786800C

申请日:

2011.01.12

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention is concerned with substituted azole derivatives thatselectively modulate, regulate, and/or inhibit signal transduction mediated bycertain native and/or mutant proteine kinases implicated in a variety of humanandanimal diseases such as cell proliferative, metabolic, allergic, anddegenerativedisorders. In particular, several of these compounds are potent and selectiveFlt-3inhibitors or/and syk inhibitors. In one embodiment, the invention provides acompound of formula (I):(see formula I)

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中国工程科技知识中心

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http://www.ckcest.cn/home/