PROBLEM TO BE SOLVED: To provide a novel low molecular weight compound that inhibits the production of amyloid beta (Aβ).SOLUTION: A compound represented by formula (I) [in the formula, the ring A represents a triazolyl group that may be substituted, or the like the ring B represents a phenyl group or the like that may be substituted, or the like X1 represents a single bond or the like R1 and R2 each represent a 1-6C alkyl group or the like m represents an integer of 0 to 3 and n represents an integer of 0 to 2], a pharmacologically acceptable salt thereof, and a pharmacologically acceptable ester thereof are effective as a therapeutic agent for a disease caused by Aβ.COPYRIGHT: (C)2012,JPO&INPIT【課題】アミロイドベータ(Aβ)の産生を抑制する新規な低分子化合物の提供。【解決手段】式(I)[式中、環Aは、置換されてもよいトリアゾリル基等を示し、環Bは、置換されてもよいフェニル基等を示し、X1は、単結合等を示し、R1及びR2は、C1-6アルキル基等を示し、mは、0-3の整数を示し、nは、0-2の整数を示す]で表される化合物又は薬理学的に許容される塩若しくはエステルは、Aβに起因する疾患の治療剤として有効である。【選択図】なし
