Mayo Foundation for Medical Education and Research
发明人:
POCKAJ, Barbara A.,BARRETT, Michael T.,BORAD, Mitesh J.,ANDERSON, Karen S.,RAMANATHAN, Ramesh K.
申请号：
EP16765644
公开号：
EP3271483A4
申请日:
2016.03.16
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
This document provides methods and materials involved in assessing cancer (e.g., breast cancer). For example, methods and materials for determining whether or not a cancer patient (e.g., a breast cancer patient) having ER−/PgR−/HER2− cancer cells is likely to have a favorable or unfavorable outcome and/or is likely to respond a cancer treatment that includes a PD-1 inhibitor and/or PD-L1 inhibitor in combination with a JAK2 inhibitor are provided. Methods and materials involved in treating mammals having ER−/PgR−/HER2− cancer (e.g., ER−/PgR−/HER2− breast cancer) by administering a PD-1 inhibitor and/or PD-L1 inhibitor in combination with a JAK2 inhibitor also are provided.
