YAROSH, DANIEL, B.,BROWN, DAVID, A.,CANNING, MATTHEW, T.
申请号:
EP05804278
公开号:
EP1784225A4
申请日:
2005.08.11
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Compositions and methods are provided for reversing and/or inhibiting inflammation, e.g., by inhibiting prostaglandin and/or COX-2 production, using one or more indolequinazoline alkaloids, preferably in combination with butylated hydroxytoluene. The preferred indolequinazoline alkaloids are rutaecarpine, evodiamine, and dehydroevodiamine, which are naturally found in unpurified form in the traditional Chinese medicine Wu Chu Yu made from the fruit of the herb, Evodia rutaecarpa.