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Combined use of gdf traps and erythropoietin receptor activators to increase red blood cell levels
专利权人:
ACCELERON PHARMA INC.
发明人:
SEEHRA JASBIR,PEARSALL ROBERT SCOTT,KUMAR RAVINDRA
申请号:
NZ59834810
公开号:
NZ598348A
申请日:
2010.08.13
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is the use of a polypeptide comprising an amino acid sequence that is at least 90% identical to the sequence of amino acids 29-109 of SEQ ID NO:1, and wherein the polypeptide comprises an acidic amino acid at the position corresponding to position 79 of SEQ ID NO:1 in the manufacture of a medicament for administration in combination with an erythropoietin receptor activator to increase red blood cell levels or to treat or prevent an anemia in a patient, wherein the sequence identity is disclosed in the specification.
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