PEPTIDE NUCLEIC ACID OF SUBGROUP J AVIAN LEUKOSIS VIRUS AND USES THEREOF

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专利权人:

Jianbao HAN

发明人:

Jianbao HAN,Bo LIU

申请号：

US15306986

公开号：

US20170189442A1

申请日:

2012.12.10

申请国别(地区):

US

年份:

2017

代理人:

摘要：

A peptide nucleic acid of subgroup J avian leukosis virus and uses of the same are provided. The sequence of the peptide nucleic acid is one or more selected from the following sequences: sequence 1: 5′AGACUAAGGCAAAAAUCUGUU-3′ sequence 2: 5′-ACGACUUAUUGAAAAACUCUC-3′ sequence 3: 5′-UAUAACCGUCUGUAGUUGGAC-3′ sequence 4: 5′-ACAUAUUUGAUUAUCUCUCCU-3′. The peptide nucleic acid, disclosed in the present invention, can specifically and directly inhibit PRRSV replication, has good antiviral effect and no drug residues, without any toxic side effect and drug resistance.

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