Disclosed are non-aqueous taxane pro-emulsion formulations are provided. Pro-emulsion formulations of embodiments of the invention include a taxane, an oil component, a surfactant component and, optionally, a non-aqueous solvent component. Also provided are methods of making and using the pro-emulsion formulations, as well as kits that include the pro-emulsion formulations. Further disclosed is a non-aqueous docetaxel liquid pro-emulsion formulation comprising: an anhydrous docetaxel or a hydrate thereof in an amount ranging from 0.1 to 5% w/w an oil component in an amount ranging from 0.3 to 5% w/w an organic acid component a surfactant component, and a non-aqueous solvent component selected from the group consisting of polyethylene glycols in an amount ranging from 15 to 65% w/w where the docetaxel liquid pro-emulsion formulation is suitable for parenteral administration to a subject, where the formulation does not include ethanol or isopropanol and where the amounts of the docetaxel and oil components differ by 50% w/w or less.
