Provided is a method for preventing or treating inflammation and associatedstates (e.g. infection, hypersensitivity, pain) by administering atherapeutically effective amount of an oxidative reduction potential (ORP)water solution that is stable for at least about twenty-four hours. The ORPwater solution administered in accordance with the invention can be combinedwith one or more suitable carriers and can be administered in conjunction withone or more additional therapeutic agents.