David R. Corey,David S. Shames,Bethany A. Janowski,John D. Minna
申请号:
US12750201
公开号:
US08324181B2
申请日:
2010.03.30
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Synthesis of a target transcript of a gene is selectively increased in a mammalian cell by contacting the cell with a polynucleotide oligomer of 12-28 bases complementary to a region within a target promoter of the gene under conditions whereby the oligomer selectively increases synthesis of the target transcript.