Disclosed in the invention is a protection device for preventing tumor dissemination and tumor metastasis in a laparoscopic surgery which comprises a soft bag (1) for containing a resected tumor during the surgery provided in the abdominal cavity through a puncture in the abdominal wall, and a sealing thread (2) provided around the mouth of the soft bag (1). The sealing cable (2) is tightened and ligated so that the mouth of the soft bag (1) is closed in the pelvic cavity or the abdominal cavity or the closed mouth of the soft bag (1) can be stretched out of the abdominal cavity through the puncture in the abdominal wall via the sealing thread (2). An instrument can be put in the soft bag in the abdominal cavity through the mouth of the soft bag (1) outside the abdominal cavity, or the instrument can be put into the soft bag in the abdominal cavity through a conduit shaped structure for a breaking operation (3) or a conduit shaped structure for an auxiliary operation (4) and the laparoscope can be put into for observation through a conduit shaped structure for peering (5). The protection device can serve as an auxiliary device in the laparoscopy surgery, in the closed abdominal cavity, a tumor tissue sample is put into the relatively closed protection device, broken and taken out under observation of the laparoscope, avoiding iatrogenic dispersion of a malignant tumor.
