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COMPOSITION PHARMACEUTIQUE À LIBÉRATION ENTRETENUE
专利权人:
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION;KOKEN CO., LTD.;KAKEN PHARMACEUTICAL CO., LTD.;KYOTO UNIVERSITY
发明人:
FUKUSHIMA, MASANORI,MATSUBARA, HIROAKI,MATOBA, SATOAKI,HIJIKATA, SHIGEKI,ASO, YU,SATO, TSUTOMU
申请号:
EP11832614
公开号:
EP2628488A4
申请日:
2011.10.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected frommonosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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