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Fusion protein comprising IL-2 protein and CD80 protein, and use thereof
专利权人:
Inc.;GI Innovation
发明人:
JANG, Myung Ho
申请号:
AU2019343850
公开号:
AU2019343850A1
申请日:
2019.09.16
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention provides a fusion protein comprising an IL-2 protein and a CD80 protein. A fusion protein comprising a CD80 fragment, an immunoglobulin Fc, and an IL-2 variant, in one embodiment, can activate immune cells, such as natural killer cells, and, at the same time, can control the immune cell regulatory activity of regulatory T cells. Therefore, a pharmaceutical composition comprising the fusion protein as an active ingredient can increase the immune activity in vivo and can be effectively used for not only cancer but also infectious diseases, and thus is highly industrially applicable.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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